Area of research
Physiology · Epidemiology
Research interest
Research interests include Adipose Tissue and Metabolism, Adipokines, Inflammation, and Metabolic Diseases, Cardiovascular Disease and Adiposity, and Peroxisome Proliferator-Activated Receptors.
Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation
Adipocyte-Secreted IL-6 Sensitizes Macrophages to IL-4 Signaling
Xanthine oxidase inhibitor urate-lowering therapy titration to target decreases serum free fatty acids in gout and suppresses lipolysis by adipocytes
FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes
Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes
<i>Chop</i> / <i>Ddit3</i> depletion in β cells alleviates ER stress and corrects hepatic steatosis in mice
TANK-Binding Kinase 1 Regulates the Localization of Acyl-CoA Synthetase ACSL1 to Control Hepatic Fatty Acid Oxidation
Catecholamines suppress fatty acid re-esterification and increase oxidation in white adipocytes via STAT3
YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity
TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue
ERRγ Preserves Brown Fat Innate Thermogenic Activity
Adapting to obesity with adipose tissue inflammation
Inhibition of IKKɛ and TBK1 Improves Glucose Control in a Subset of Patients with Type 2 Diabetes
Lipotoxicity induces hepatic protein inclusions through TANK binding kinase 1–mediated p62/sequestosome 1 phosphorylation
Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance
An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice