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William G. Kaelin

Harvard University · US
🔎 Find collaborators in Cancer Research · Molecular Biology →
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Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Cancer, Hypoxia, and Metabolism, Cancer-related Molecular Pathways, Epigenetics and DNA Methylation, and Renal cell carcinoma treatment.
h-index
138
citations
68,532
works
497
NIH funding
primary concept
Biology
email

Recent publications

Targeting of HIF2-driven cachexia in kidney cancer.
2026cited by 3position: contributordoi
Publisher Correction: argeting of HIF2-driven cachexia in kidney cancer.
2026cited by 0position: contributordoi
HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy
Cell 2025cited by 52position: contributordoi
HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy
Cell 2025cited by 49position: lastdoi
Targeting of HIF2-driven cachexia in kidney cancer
Nature Medicine 2025cited by 6position: lastdoi
Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
Cancer Discovery 2025cited by 6position: lastdoi
Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer.
2025cited by 5position: contributordoi
The SLC1A1/EAAT3 dicarboxylic amino acid transporter is an epigenetically dysregulated nutrient carrier that sustains oncogenic metabolic programs.
2025cited by 4position: contributordoi
The SLC1A1/EAAT3 dicarboxylic amino acid transporter is an epigenetically dysregulated nutrient carrier that sustains oncogenic metabolic programs
Nature Communications 2025cited by 2position: middledoi
Making sense of low-complexity domains: The 2025 Lasker Basic Science Award.
2025cited by 1position: contributordoi
HIF2-driven PTHrP Causes Cachexia and Hypercalcemia in Kidney Cancer: Treatment with HIF2 Inhibitors
2025cited by 1position: contributordoi
Positive Selection Screen Identifies Natural Product β-Catenin Inactivators
2025cited by 1position: contributordoi
Shirole Fig. S1 from Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
2025cited by 0position: contributordoi
Shirole Fig. S9 from Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
2025cited by 0position: contributordoi
Shirole Fig. S3 from Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
2025cited by 0position: contributordoi
Shirole Fig. S15 from Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
2025cited by 0position: contributordoi
Shirole Fig. S10 from Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
2025cited by 0position: contributordoi
Table S4 from Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
2025cited by 0position: contributordoi
Table S5 from Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
2025cited by 0position: contributordoi
Shirole Fig. S4 from Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
2025cited by 0position: contributordoi
Table S6 from Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
2025cited by 0position: contributordoi
Shirole Fig. S2 from Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
2025cited by 0position: contributordoi
Shirole Fig. S14 from Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
2025cited by 0position: contributordoi
Data from Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
2025cited by 0position: contributordoi
Shirole Fig. S12 from Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
2025cited by 0position: contributordoi
Table S1 from Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
2025cited by 0position: contributordoi
Shirole Fig. S5 from Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
2025cited by 0position: contributordoi
Shirole Fig. S13 from Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
2025cited by 0position: contributordoi
Table S8 from Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
2025cited by 0position: contributordoi
Shirole Fig. S6 from Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
2025cited by 0position: contributordoi

Grants

No grants ingested yet.

Frequent collaborators

· 41 papers (2019–2026)Nitin H. Shirole · Stony Brook University26 papers (2025–2025)John G. Doench · Broad Institute26 papers (2021–2025)Seth R. Goldman · Ackerman Institute for the Family25 papers (2025–2025)Karen Adelman · Rockefeller University25 papers (2025–2025)Shweta Kukreja · University of Massachusetts Chan Medical School25 papers (2025–2025)Henry Long · Sun Yat-sen University Cancer Center25 papers (2025–2025)Devishi Kesar · Massachusetts Institute of Technology25 papers (2025–2025)Paloma Cejas · University of Cincinnati Medical Center25 papers (2025–2025)William R. Sellers · Cancer Research Center25 papers (2025–2025)Xintao Qiu · Fuzhou University25 papers (2025–2025)Sudeepa Syamala · University of Cincinnati Medical Center25 papers (2025–2025)Amy Goodale · Massachusetts Institute of Technology25 papers (2025–2025)Rong Li · University of South China25 papers (2025–2025)Yenarae Lee · Broad Institute25 papers (2025–2025)WENYU YU · Harvard University25 papers (2025–2025)Sabina Signoretti · Cancer Research Center9 papers (2013–2019) · 7 papers (2012–2020)Abhishek A. Chakraborty · Case Western Reserve University7 papers (2016–2022)Samuel K. McBrayer · Dana-Farber Brigham Cancer Center6 papers (2017–2025)
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