Area of research
Cancer Research · Cell Biology
Research interest
Research interests include Cancer research, Biology, Chemistry, Cell biology, Clear cell renal cell carcinoma, and Kinase.
The SLC1A1/EAAT3 dicarboxylic amino acid transporter is an epigenetically dysregulated nutrient carrier that sustains oncogenic metabolic programs
Chronic hypoxia stabilizes 3βHSD1 via autophagy suppression
GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity
A Mesenchymal Tumor Cell State Confers Increased Dependency on the BCL-XL Antiapoptotic Protein in Kidney Cancer
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
Mutant p53 induces a hypoxia transcriptional program in gastric and esophageal adenocarcinoma
Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma
Cells Lacking the <i>RB1</i> Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival
HIF activation causes synthetic lethality between the <i>VHL</i> tumor suppressor and the <i>EZH1</i> histone methyltransferase
On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
A common functional consequence of tumor-derived mutations within c-MYC