Area of research
Molecular Biology · Plant Science
Research interest
Research focused on Mitochondrial DNA and Chromatin, with related work in Mitochondrion, Genome, Cell biology. Notable publications include 'Nuclear sensing of breaks in mitochondrial DNA enhances immune surveillance', 'Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia', and 'CRISPR-dCas9 and sgRNA scaffolds enable dual-colour live imaging of satellite sequences and repeat-enriched individual loci'.
Engineering mtDNA deletions by reconstituting end joining in human mitochondria
Mitochondrial DNA breaks activate an integrated stress response to reestablish homeostasis
Nuclear sensing of breaks in mitochondrial DNA enhances immune surveillance
Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia
Safeguarding mitochondrial genomes in higher eukaryotes
Kindlin-2 deficiency induces fatal intestinal obstruction in mice
VEGF amplifies transcription through ETS1 acetylation to enable angiogenesis
CRISPR-dCas9 and sgRNA scaffolds enable dual-colour live imaging of satellite sequences and repeat-enriched individual loci
4C-ker: A Method to Reproducibly Identify Genome-Wide Interactions Captured by 4C-Seq Experiments
A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination