Area of research
Molecular Biology · Pulmonary and Respiratory Medicine
Research interest
Research focused on Enhancer and Chromatin, with related work in Cell biology, Computational biology, Transcription factor. Notable publications include 'An Erythroid Enhancer of BCL11A Subject to Genetic Variation Determines Fetal Hemoglobin Level', 'MAnorm: a robust model for quantitative comparison of ChIP-Seq data sets', and 'In Situ Capture of Chromatin Interactions by Biotinylated dCas9'.
Regulation of embryonic haematopoietic multipotency by EZH1
In Situ Capture of Chromatin Interactions by Biotinylated dCas9
Regulation of mitochondrial biogenesis in erythropoiesis by mTORC1-mediated protein translation
Functional analysis reveals that RBM10 mutations contribute to lung adenocarcinoma pathogenesis by deregulating splicing
Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis
Developmental Control of Polycomb Subunit Composition by GATA Factors Mediates a Switch to Non-Canonical Functions
PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells
An Erythroid Enhancer of <i>BCL11A</i> Subject to Genetic Variation Determines Fetal Hemoglobin Level
Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation
Distinct and Combinatorial Functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in Mouse Embryonic Stem Cell Identity
GATA1s induces hyperproliferation of eosinophil precursors in Down syndrome transient leukemia
MAnorm: a robust model for quantitative comparison of ChIP-Seq data sets
Combinatorial Assembly of Developmental Stage-Specific Enhancers Controls Gene Expression Programs during Human Erythropoiesis