← back to search

David B. Thompson

Harvard University · US
Area of research
Molecular Biology · Genetics
Research interest
Research interests include CRISPR and Genetic Engineering, RNA Interference and Gene Delivery, Advanced biosensing and bioanalysis techniques, and RNA and protein synthesis mechanisms.
h-index
24
citations
5,354
works
39
NIH funding
primary concept
email

Recent publications

Treatment of monogenic and digenic dominant genetic hearing loss by CRISPR-Cas9 ribonucleoprotein delivery in vivo
Nature Communications 2023cited by 46position: middledoi
Multisystem inflammatory syndrome in children is driven by zonulin-dependent loss of gut mucosal barrier
Journal of Clinical Investigation 2021cited by 255position: middledoi
RNA-responsive elements for eukaryotic translational control
Nature Biotechnology 2021cited by 100position: middledoi
The case for biotech on Mars
Nature Biotechnology 2020cited by 103position: middledoi
High-resolution specificity profiling and off-target prediction for site-specific DNA recombinases
Nature Communications 2019cited by 45position: middledoi
An anionic human protein mediates cationic liposome delivery of genome editing proteins into mammalian cells
Nature Communications 2019cited by 35position: middledoi
Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents
Nature 2017cited by 536position: middledoi
A programmable Cas9-serine recombinase fusion protein that operates on DNA sequences in mammalian cells
Nucleic Acids Research 2016cited by 58position: middledoi
Small molecule–triggered Cas9 protein with improved genome-editing specificity
Nature Chemical Biology 2015cited by 432position: middledoi
Discovery and Characterization of a Peptide That Enhances Endosomal Escape of Delivered Proteins in Vitro and in Vivo
Journal of the American Chemical Society 2015cited by 133position: middledoi
Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo
Nature Biotechnology 2014cited by 1,464position: middledoi
Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification
Nature Biotechnology 2014cited by 845position: middledoi
Engineering and Identifying Supercharged Proteins for Macromolecule Delivery into Mammalian Cells
Methods in enzymology on CD-ROM/Methods in enzymology 2012cited by 130position: firstdoi
Cellular Uptake Mechanisms and Endosomal Trafficking of Supercharged Proteins
Chemistry & Biology 2012cited by 103position: firstdoi

Grants

NSFGEO-NERC: Analyses of the Pattern Effect on Radiative Feedbacks: Gaining Physical Insights from Statistical Methods; Testing the Role of Land Surface Temperatures
NSF2507587$1,030,0412025–2028PIRePORTER
Understanding the Influence of Climate Change on Temperature Persistence
NSF2116186$795,2022021–2025PIRePORTER
Collaborative Research: Understanding the Role of Coupled Chemistry-climate Interactions in Internal Climate Variability
NSF1848785$523,6782019–2023PIRePORTER
CHS: Small: Enhancing EEG-based Emotion Estimation with Transfer Learning, Priming, and Virtual Reality
NSF1910526$499,9732019–2024PIRePORTER
Analyses of Large-scale Climate Variability: Understanding Periodicity in the Extratropical Storm Tracks
NSF1734251$697,8612017–2021PIRePORTER
Aspects of the Dynamics of the Coupled Tropsphere-Stratosphere System
NSF1643167$637,7412017–2021PIRePORTER
Understanding Two-way Coupling Between Cloud Radiative Effects and the Large-Scale Extratropical Atmospheric Circulation
NSF1547003$635,6032016–2020PIRePORTER
Analyses of Large-scale Extratropical Climate Variability and Change
NSF1343080$738,6322014–2018PIRePORTER
G&V: Medium: Collaborative Research: Large Data Visualization Using An Interactive Machine Learning Framework
NSF1065107$280,2582011–2015PIRePORTER
Analyses of Large-Scale Climate Variability
NSF0936255$823,1462010–2013PIRePORTER
Support for a Symposium to Honor Mike Wallace's Contributions to the Field of Climate Dynamics; Seattle, Washington; September 27-28, 2010
NSF1041770$20,0002010–2011PIRePORTER
Analyses of Climate Variability and Climate Change
NSF0613082$449,5122006–2010PIRePORTER
Analysis of Annular Variability in the Global Circulation
NSF0320959$319,4602003–2007PIRePORTER
CAREER: Analysis of the Southern Hemisphere Annular Mode and Its Role in Climate Change
NSF0132190$400,0002002–2008PIRePORTER
Hydraulic Servo-Mechanisms with Nonlinear Mechanical Loads: Robust Performance with Analysis and Control of Bifurcation Behavior
NSF9978704$169,9632000–2004PIRePORTER
New Materials for Coupling Electron and Ion Transfer Across Model Archaebacterial Membranes
NSF9319099$230,0001994–1999PIRePORTER
Carbon-Carbon Bond-Forming Reactions: Application to the Selective Synthesis of Alkenols and Cyclic Ethers
NSF8822097$97,0881989–1993PIRePORTER
The Synthesis of Pyrans Via the Lewis Acid Promoted Cyclization of Unsaturated Acetals (Chemistry)
NSF8512477$73,6801985–1989PIRePORTER
Acquisition of Gas Chromatograph and Accessories
NSF8114795$15,1401982–1983PIRePORTER
Instructional Scientific Equipment Program
NSF7511008$15,1001975–1977PIRePORTER

Frequent collaborators

David R. Liu · Broad Institute11 papers (2012–2023)Johnny H. Hu · Broad Institute4 papers (2014–2023)Yilai Shu · Fudan University4 papers (2014–2023)Zheng‐Yi Chen · Fudan University4 papers (2014–2023)Yong Tao · First Affiliated Hospital of Wannan Medical College3 papers (2015–2023)John A. Zuris · Editas Medicine (United States)3 papers (2014–2023)Jeffrey L. Bessen · Health Advances (United States)3 papers (2014–2019)John P. Guilinger · Boston Engineering (United States)2 papers (2014–2014)Xue Gao · Jiangsu University2 papers (2017–2023)Verónica Lamas · Salk Institute for Biological Studies2 papers (2017–2023)Weijia Kong · Wuhan Union Hospital2 papers (2017–2023) · 1 papers (2020–2020)Xuezhong Liu · University of Miami1 papers (2023–2023)James J. Cronican · Takeda (United States)1 papers (2012–2012)Madelynn N. Whittaker · Cardiovascular Institute of the South1 papers (2023–2023)Nathaniel D. Tippens · Cornell University1 papers (2021–2021)J. Keith Joung · Harvard University1 papers (2014–2014) · 1 papers (2023–2023)Mingqian Huang · Nanjing Medical University1 papers (2017–2017) · 1 papers (2012–2012)