Area of research
Molecular Biology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Ferroptosis and cancer prognosis, RNA modifications and cancer, Cancer, Lipids, and Metabolism, and Epigenetics and DNA Methylation.
Interleukin-16 enhances anti-tumor immune responses by establishing a Th1 cell-macrophage crosstalk through reprogramming glutamine metabolism in mice
DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs
TGF-β in the microenvironment induces a physiologically occurring immune-suppressive senescent state
Downregulation of KEAP1 in melanoma promotes resistance to immune checkpoint blockade
RNA transcripts stimulate homologous recombination by forming DR-loops
NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer
The Lipogenic Regulator SREBP2 Induces Transferrin in Circulating Melanoma Cells and Suppresses Ferroptosis
Epithelial to mesenchymal plasticity and differential response to therapies in pancreatic ductal adenocarcinoma
SETD1A protects from senescence through regulation of the mitotic gene expression program
Single-cell multiomics sequencing and analyses of human colorectal cancer
Bisulfite-Free, Nanoscale Analysis of 5-Hydroxymethylcytosine at Single Base Resolution
Single-Cell RNA-Seq Analysis Maps Development of Human Germline Cells and Gonadal Niche Interactions
Single-cell DNA methylome sequencing of human preimplantation embryos
DNA methylation and chromatin accessibility profiling of mouse and human fetal germ cells
The Transcriptome and DNA Methylome Landscapes of Human Primordial Germ Cells
Epigenomic Landscape of Human Fetal Brain, Heart, and Liver
The DNA methylation landscape of human early embryos
Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain
Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells