Area of research
Hepatology · Epidemiology
Research interest
Research interests include Liver physiology and pathology, Liver Disease Diagnosis and Treatment, Gene Regulatory Network Analysis, and PI3K/AKT/mTOR signaling in cancer.
Basal MET phosphorylation is an indicator of hepatocyte dysregulation in liver disease
Lysis buffer selection guidance for mass spectrometry-based global proteomics including studies on the intersection of signal transduction and metabolism
Tolerance of repeated toxic injuries of murine livers is associated with steatosis and inflammation
Deciphering signal transduction networks in the liver by mechanistic mathematical modelling
Automated Detection of Portal Fields and Central Veins in Whole-Slide Images of Liver Tissue
Tolerance of repeated toxic injuries of murine livers is associated with steatosis and inflammation
Repeated toxic injuries of murine liver are tolerated through microsteatosis and mild inflammation
Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib
Context-specific flow through the MEK/ERK module produces cell- and ligand-specific patterns of ERK single and double phosphorylation
T160‐phosphorylated CDK2 defines threshold for HGF‐dependent proliferation in primary hepatocytes
Disentangling the Complexity of HGF Signaling by Combining Qualitative and Quantitative Modeling
Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling
Hepatocellular carcinoma: a systems biology perspective
Biological Foundations of Signal Transduction, Systems Biology and Aberrations in Disease
Excemplify: A Flexible Template Based Solution, Parsing and Managing Data in Spreadsheets for Experimentalists
Heterogeneous kinetics of AKT signaling in individual cells are accounted for by variable protein concentration
Cellular ERK Phospho-Form Profiles with Conserved Preference for a Switch-Like Pattern