Area of research
Hepatology · Epidemiology
Research interest
Research interests include Biology, Cell biology, Hepatocyte, Gene, Computational biology, and Chemistry.
Basal MET phosphorylation is an indicator of hepatocyte dysregulation in liver disease
SARS-CoV-2 mRNA vaccination–induced immunological memory in human nonlymphoid and lymphoid tissues
Diploid hepatocytes drive physiological liver renewal in adult humans
Correction to: Toxicogenomics directory of chemically exposed human hepatocytes
Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis
Disentangling molecular mechanisms regulating sensitization of interferon alpha signal transduction
Long-term simulation of lead concentrations in agricultural soils in relation to human adverse health effects
Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses
Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses
Resolving the Combinatorial Complexity of Smad Protein Complex Formation and Its Link to Gene Expression
A unifying mathematical model of lipid droplet metabolism reveals key molecular players in the development of hepatic steatosis
Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib
Bile canaliculi formation and biliary transport in 3D sandwich-cultured hepatocytes in dependence of the extracellular matrix composition
Context-specific flow through the MEK/ERK module produces cell- and ligand-specific patterns of ERK single and double phosphorylation
Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells
Corrigendum to “Gene networks and transcription factor motifs defining the differentiation of human stem cells into hepatocyte-like cells” [J Hepatol 2015;63:934–942]
Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells
Transcriptional regulatory networks governing stem cell differentiation into hepatocytes in vitro
Toxicogenomics directory of chemically exposed human hepatocytes
Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME
Direct Transcriptional Regulation of Human Hepatic Cytochrome P450 3A4 (CYP3A4) by Peroxisome Proliferator–Activated Receptor Alpha (PPARα)