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Yuan Hou

Cleveland Clinic Lerner College of Medicine · US
🔎 Find collaborators in Neurology · Molecular Biology →
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Area of research
Neurology · Molecular Biology
Research interest
Research focused on Interactome and Computational biology, with related work in Drug repositioning, Traumatic brain injury, Neuroinflammation. Notable publications include 'Comprehensive characterization of protein–protein interactions perturbed by disease mutations', 'Reducing acetylated tau is neuroprotective in brain injury', and 'A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets'.
h-index
citations
994
works
7
NIH funding
primary concept
email

Recent publications

A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets
Nature Biotechnology 2022cited by 196position: middledoi
Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer’s disease
Cell Reports 2022cited by 100position: middledoi
Comprehensive characterization of protein–protein interactions perturbed by disease mutations
Nature Genetics 2021cited by 243position: middledoi
Reducing acetylated tau is neuroprotective in brain injury
Cell 2021cited by 216position: middledoi
Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment
Alzheimer s Research & Therapy 2021cited by 162position: middledoi
A Systems Pharmacology Approach Uncovers Wogonoside as an Angiogenesis Inhibitor of Triple-Negative Breast Cancer by Targeting Hedgehog Signaling
Cell chemical biology 2019cited by 71position: middledoi
Target Identification Among Known Drugs by Deep Learning from Heterogeneous Networks
SSRN Electronic Journal 2019cited by 6position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Feixiong Cheng · Cleveland Clinic Lerner College of Medicine6 papers (2019–2022)Yadi Zhou · East China University of Science and Technology5 papers (2019–2022)Charis Eng · Cardiovascular Institute of the South4 papers (2019–2022)Weiqiang Lü · Texas A&M University3 papers (2019–2021)Jiansong Fang · Guangzhou University of Chinese Medicine3 papers (2019–2021)Justin D. Lathia · University of Alabama at Birmingham2 papers (2019–2021)Lara Jehi · Cleveland Clinic2 papers (2021–2022)Ruth Nussinov · Tel Aviv University2 papers (2019–2019)Joseph Loscalzo · Broad Institute2 papers (2019–2021)James B. Leverenz · Cleveland Clinic2 papers (2021–2022)Haiyuan Yu · Cornell University2 papers (2021–2022)Andrew A. Pieper · University Hospitals of Cleveland2 papers (2021–2022)Jin Huang · Shanghai University2 papers (2019–2021)Chengsheng Mao · Case Western Reserve University2 papers (2022–2022)Yuan Luo · Guangzhou University of Chinese Medicine2 papers (2022–2022)Jielin Xu · The Ohio State University2 papers (2021–2022)Pei‐Hui Wang · Hebei Medical University1 papers (2022–2022)Ming Hu · Case Western Reserve University1 papers (2022–2022)Margaret E. Flanagan · The University of Texas at San Antonio Health Science Center1 papers (2022–2022)Mriganka Nerkar · Cornell University1 papers (2022–2022)
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