Area of research
Immunology · Radiology, Nuclear Medicine and Imaging
Research interest
Research interests include Biology, Germinal center, Cancer research, Immunology, FOXO1, and Cell biology.
Precise CRISPR-Cas9 gene repair in autologous memory T cells to treat familial hemophagocytic lymphohistiocytosis
An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets
Transcriptional reprogramming by mutated IRF4 in lymphoma
Mouse models of human multiple myeloma subgroups
Precise CRISPR-Cas–mediated gene repair with minimal off-target and unintended on-target mutations in human hematopoietic stem cells
Concomitant Cytotoxic Effector Differentiation of CD4+ and CD8+ T Cells in Response to EBV-Infected B Cells
Efficient CRISPR-Cas9-mediated mutagenesis in primary human B cells for identifying plasma cell regulators
A new type of transcriptional reprogramming by an IRF4 mutation in lymphoma
The magnitude of germinal center reactions is restricted by a fixed number of preexisting niches
Immunoglobulin expression in the endoplasmic reticulum shapes the metabolic fitness of B lymphocytes
B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage
Postnatal DNA demethylation and its role in tissue maturation
Nuclear FOXO1 promotes lymphomagenesis in germinal center B cells
EBI2 Is Highly Expressed in Multiple Sclerosis Lesions and Promotes Early CNS Migration of Encephalitogenic CD4 T Cells
FOXO1 couples metabolic activity and growth state in the vascular endothelium
miR-23∼27∼24 clusters control effector T cell differentiation and function
Tissue-specific DNA demethylation is required for proper B-cell differentiation and function
A c-Myc/miR17-92/Pten Axis Controls PI3K-Mediated Positive and Negative Selection in B Cell Development and Reconstitutes CD19 Deficiency
miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation
miRNAs are critical for the regulation of RAG expression and secondary Ig rearrangement in peripheral B lymphocytes
Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma
PI3 Kinase and FOXO1 Transcription Factor Activity Differentially Control B Cells in the Germinal Center Light and Dark Zones
An Oncogenic Role for Alternative NF-κB Signaling in DLBCL Revealed upon Deregulated BCL6 Expression
A Rapid Embryonic Stem Cell–Based Mouse Model for B-cell Lymphomas Driven by Epstein–Barr Virus Protein LMP1
<scp>TET</scp> proteins and 5‐methylcytosine oxidation in hematological cancers
STAT3 Activation in Th17 and Th22 Cells Controls IL-22–Mediated Epithelial Host Defense during Infectious Colitis
Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma
T Cell–Derived IL-17 Mediates Epithelial Changes in the Airway and Drives Pulmonary Neutrophilia
The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers
Synergy between PI3K Signaling and MYC in Burkitt Lymphomagenesis