Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Genomics and Chromatin Dynamics, Chromatin Remodeling and Cancer, Cancer Genomics and Diagnostics, and PI3K/AKT/mTOR signaling in cancer.
In vivo base editing extends lifespan of a humanized mouse model of prion disease
Prime editing-installed suppressor tRNAs for disease-agnostic genome editing
Efficient site-specific integration of large genes in mammalian cells via continuously evolved recombinases and prime editing
ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis
Author Correction: ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis
CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities
Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program
Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion
Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells