Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Cancer Genomics and Diagnostics, Single-cell and spatial transcriptomics, Genomics and Chromatin Dynamics, and Glycosylation and Glycoproteins Research.
Three-dimensional genome landscape of primary human cancers
Single-cell chromatin accessibility reveals malignant regulatory programs in primary human cancers
ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis
ecDNA hubs drive cooperative intermolecular oncogene expression
Author Correction: ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis
Single-cell epigenomic analyses implicate candidate causal variants at inherited risk loci for Alzheimer’s and Parkinson’s diseases
Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity
Clonal replacement of tumor-specific T cells following PD-1 blockade
Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion
c-Jun overexpression in CAR T cells induces exhaustion resistance
Circular ecDNA promotes accessible chromatin and high oncogene expression
Single-cell multiomic analysis identifies regulatory programs in mixed-phenotype acute leukemia
GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways
Cryptic activation of an Irf8 enhancer governs cDC1 fate specification
An Nfil3–Zeb2–Id2 pathway imposes Irf8 enhancer switching during cDC1 development
HiChIRP reveals RNA-associated chromosome conformation
The chromatin accessibility landscape of primary human cancers
Transcript-indexed ATAC-seq for precision immune profiling
Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements