Area of research
Virology · Radiology, Nuclear Medicine and Imaging
Research interest
Research interests include HIV Research and Treatment, Monoclonal and Polyclonal Antibodies Research, HIV/AIDS drug development and treatment, and thermodynamics and calorimetric analyses.
Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site
Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies
Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains
A Potent Anti-Malarial Human Monoclonal Antibody Targets Circumsporozoite Protein Minor Repeats and Neutralizes Sporozoites in the Liver
Targeting the pregnane X receptor using microbial metabolite mimicry
Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization
Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite
Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529
The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions
Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus <i>ex Vivo</i> and Distribution <i>in Vivo</i>
Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
CD4 mimetics sensitize HIV-1-infected cells to ADCC
Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env