Area of research
Molecular Biology · Materials Chemistry
Research interest
Research interests include Enzyme Structure and Function, Protein Structure and Dynamics, Metal-Catalyzed Oxygenation Mechanisms, and Photosynthetic Processes and Mechanisms.
Conformational landscapes of a class I ribonucleotide reductase complex during turnover reveal intrinsic dynamics and asymmetry
Mechanistic manifold in a hemoprotein-catalyzed cyclopropanation reaction with diazoketone
Tuning Enzyme Thermostability via Computationally Guided Covalent Stapling and Structural Basis of Enhanced Stabilization
Small-angle X-ray scattering studies of enzymes
The Molecular Basis for Life in Extreme Environments
Diffuse X-ray scattering from correlated motions in a protein crystal
Allosteric Inhibition of Human Ribonucleotide Reductase by dATP Entails the Stabilization of a Hexamer
Synchrotron-based small-angle X-ray scattering of proteins in solution
Generation of a stable, aminotyrosyl radical-induced α2β2 complex of <i>Escherichia coli</i> class Ia ribonucleotide reductase
Crystallographic snapshots of metalloenzyme complexes involved in biological carbon dioxide sequestration
Visualizing molecular juggling within a B12-dependent methyltransferase complex
Tangled Up in Knots: Structures of Inactivated Forms of E. coli Class Ia Ribonucleotide Reductase
Transient B<sub>12</sub>-Dependent Methyltransferase Complexes Revealed by Small-Angle X-ray Scattering