Area of research
Genetics · Molecular Biology
Research interest
Research interests include Genetic Associations and Epidemiology, Epigenetics and DNA Methylation, Genomics and Rare Diseases, and Bioinformatics and Genomic Networks.
Brain expression quantitative trait locus and network analyses reveal downstream effects and putative drivers for brain-related diseases
OTTERS: a powerful TWAS framework leveraging summary-level reference data
KidneyNetwork: using kidney-derived gene expression data to predict and prioritize novel genes involved in kidney disease
Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
Mapping the human genetic architecture of COVID-19
Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology
Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour
DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan
TAB2 deletions and variants cause a highly recognisable syndrome with mitral valve disease, cardiomyopathy, short stature and hypermobility
Deconvolution of bulk blood eQTL effects into immune cell subpopulations
Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference
Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits
Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances
Associations of autozygosity with a broad range of human phenotypes
Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults
Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes
Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis
Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood
CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits
Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity
The effect of host genetics on the gut microbiome
Identification of context-dependent expression quantitative trait loci in whole blood
A Functional Genomics Approach to Understand Variation in Cytokine Production in Humans
A high-quality human reference panel reveals the complexity and distribution of genomic structural variants
Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps
RNA Sequencing Analysis of Intracranial Aneurysm Walls Reveals Involvement of Lysosomes and Immunoglobulins in Rupture
TMEM258 Is a Component of the Oligosaccharyltransferase Complex Controlling ER Stress and Intestinal Inflammation
Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations
Lessons Learned from Whole Exome Sequencing in Multiplex Families Affected by a Complex Genetic Disorder, Intracranial Aneurysm