Area of research
Hematology · Molecular Biology
Research interest
Research interests include Acute Myeloid Leukemia Research, Epigenetics and DNA Methylation, MicroRNA in disease regulation, and Cancer Genomics and Diagnostics.
Multi-dimensional analysis of adult acute myeloid leukemia cross-continents reveals age-associated trends in mutational landscape and treatment outcomes (Acute Myeloid Leukemia Cooperative Group & Alliance for Clinical Trials in Oncology)
CSF3R T618I Collaborates With RUNX1-RUNX1T1 to Expand Hematopoietic Progenitors and Sensitizes to GLI Inhibition
ZBTB7A Loss Promotes Synthesis of Lipids and Ketone Bodies in Myeloid Leukemia
Specific effects of somatic GATA2 zinc finger mutations on erythroid differentiation
Leukemia Cell of Origin Influences Apoptotic Priming and Sensitivity to LSD1 Inhibition
ZBTB7A prevents RUNX1-RUNX1T1-dependent clonal expansion of human hematopoietic stem and progenitor cells
GATA2 Zinc Finger Mutations Influence Erythroid Differentiation and Chemotherapy Response
GATA2 Zinc Finger Mutations Affect DNA-Binding and Promote Granulopoietic Differentiation
Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in <i>NPM1</i> Mutant Leukemia
Controlled stem cell amplification by HOXB4 depends on its unique proline-rich region near the N terminus
Hematopoietic Differentiation Is Required for Initiation of Acute Myeloid Leukemia