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Nancy U. Lin

San Francisco Art Institute · US
Area of research
Pulmonary and Respiratory Medicine · Oncology
Research interest
Research interests include Advanced Breast Cancer Therapies, Brain Metastases and Treatment, Breast Cancer Treatment Studies, and HER2/EGFR in Cancer Research.
h-index
95
citations
42,587
works
1,051
NIH funding
primary concept
email

Recent publications

RANO criteria for response assessment of brain metastases based on amino acid PET imaging
Nature Medicine 2025cited by 22position: middledoi
Contrastive learning enhances fairness in pathology artificial intelligence systems
Cell Reports Medicine 2025cited by 4position: middledoi
Author Correction: A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features
Nature Medicine 2025cited by 0position: middledoi
A pathology foundation model for cancer diagnosis and prognosis prediction
Nature 2024cited by 396position: middledoi
Trastuzumab deruxtecan in HER2-positive advanced breast cancer with or without brain metastases: a phase 3b/4 trial
Nature Medicine 2024cited by 172position: middledoi
A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features
Nature Medicine 2024cited by 70position: middledoi
Exemestane plus everolimus and palbociclib in metastatic breast cancer: clinical response and genomic/transcriptomic determinants of resistance in a phase I/II trial
Nature Communications 2024cited by 26position: middledoi
SACI-IO HR+: A randomized phase II trial of sacituzumab govitecan with or without pembrolizumab in patients with metastatic hormone receptor-positive/HER2-negative breast cancer.
Journal of Clinical Oncology 2024cited by 25position: middledoi
Correlation of serum anti-Müllerian hormone (AMH) levels on identification of premenopausal patients (pts) with hormone receptor positive (HR+), HER2-negative, node-positive breast cancer most likely to benefit from adjuvant chemotherapy in SWOG S1007 (RxPONDER).
Journal of Clinical Oncology 2024cited by 19position: middledoi
Tucatinib-trastuzumab-capecitabine for treatment of leptomeningeal metastasis in HER2+ breast cancer: TBCRC049 phase 2 study results.
Journal of Clinical Oncology 2024cited by 11position: middledoi
Comprehensive genomic characterization of HER2-low and HER2-0 breast cancer
Nature Communications 2023cited by 59position: lastdoi
STING agonism reprograms tumor-associated macrophages and overcomes resistance to PARP inhibition in BRCA1-deficient models of breast cancer
Nature Communications 2022cited by 242position: middledoi
Tucatinib vs Placebo, Both in Combination With Trastuzumab and Capecitabine, for Previously Treated ERBB2 (HER2)-Positive Metastatic Breast Cancer in Patients With Brain Metastases
JAMA Oncology 2022cited by 190position: firstdoi
Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis
Nature Cancer 2022cited by 112position: middledoi
A phase I/II study of intrathecal trastuzumab in human epidermal growth factor receptor 2-positive (HER2-positive) cancer with leptomeningeal metastases: Safety, efficacy, and cerebrospinal fluid pharmacokinetics
Neuro-Oncology 2022cited by 74position: middledoi
Development and Validation of a Predictive Model of Severe Fatigue After Breast Cancer Diagnosis: Toward a Personalized Framework in Survivorship Care
Journal of Clinical Oncology 2022cited by 59position: middledoi
Long-Term Longitudinal Patterns of Patient-Reported Fatigue After Breast Cancer: A Group-Based Trajectory Analysis
Journal of Clinical Oncology 2022cited by 54position: middledoi
Abstract PD4-02: Safety and efficacy of a tucatinib-trastuzumab-capecitabine regimen for treatment of leptomeningeal metastasis (LM) in HER2-positive breast cancer: Results from TBCRC049, a phase 2 non-randomized study
Cancer Research 2022cited by 27position: middledoi
Evaluation of a Liquid Biopsy-Breast Cancer Methylation (LBx-BCM) Cartridge Assay for Predicting Early Disease Progression and Survival: TBCRC 005 Prospective Trial
Clinical Cancer Research 2022cited by 16position: middledoi
Abstract GS3-00: First results from a phase III randomized clinical trial of standard adjuvant endocrine therapy (ET) +/- chemotherapy (CT) in patients (pts) with 1-3 positive nodes, hormone receptor-positive (HR+) and HER2-negative (HER2-) breast cancer (BC) with recurrence score (RS) < 25: SWOG S1007 (RxPonder)
Cancer Research 2021cited by 88position: middledoi
Molecular correlates of response to eribulin and pembrolizumab in hormone receptor-positive metastatic breast cancer
Nature Communications 2021cited by 47position: middledoi
Pharmacokinetic (PK) analyses in CSF and plasma from TBCRC049, an ongoing trial to assess the safety and efficacy of the combination of tucatinib, trastuzumab and capecitabine for the treatment of leptomeningeal metastasis (LM) in HER2 positive breast cancer.
Journal of Clinical Oncology 2021cited by 30position: middledoi
Sociodemographic Factors Associated With Rapid Relapse in Triple-Negative Breast Cancer: A Multi-Institution Study
Journal of the National Comprehensive Cancer Network 2021cited by 22position: middledoi
Intracranial Efficacy and Survival With Tucatinib Plus Trastuzumab and Capecitabine for Previously Treated HER2-Positive Breast Cancer With Brain Metastases in the HER2CLIMB Trial
Journal of Clinical Oncology 2020cited by 541position: firstdoi
TBCRC 048: Phase II Study of Olaparib for Metastatic Breast Cancer and Mutations in Homologous Recombination-Related Genes
Journal of Clinical Oncology 2020cited by 492position: middledoi
Survival in Patients With Brain Metastases: Summary Report on the Updated Diagnosis-Specific Graded Prognostic Assessment and Definition of the Eligibility Quotient
Journal of Clinical Oncology 2020cited by 450position: middledoi
The Genomic Landscape of Intrinsic and Acquired Resistance to Cyclin-Dependent Kinase 4/6 Inhibitors in Patients with Hormone Receptor–Positive Metastatic Breast Cancer
Cancer Discovery 2020cited by 427position: middledoi
Prevalence and mutational determinants of high tumor mutation burden in breast cancer
Annals of Oncology 2020cited by 356position: middledoi
HER2-Mediated Internalization of Cytotoxic Agents in <i>ERBB2</i> Amplified or Mutant Lung Cancers
Cancer Discovery 2020cited by 282position: middledoi
Consensus recommendations for a standardized brain tumor imaging protocol for clinical trials in brain metastases
Neuro-Oncology 2020cited by 255position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Eric P. Winer · Yale University10 papers (2013–2022)Antonio C. Wolff · Technical University of Denmark10 papers (2014–2024)Patrick Y. Wen · Harvard University9 papers (2013–2020)Rita Nanda · Sun Pharma (India)8 papers (2014–2024)F. Stephen Hodi · Harvard University7 papers (2013–2020)Michelle Melisko · UCSF Helen Diller Family Comprehensive Cancer Center7 papers (2014–2024)Ian E. Krop · Cancer Institute (WIA)7 papers (2015–2024)Eudocia Q. Lee · Center for Neuro-Oncology7 papers (2013–2022)Anna Maria Storniolo · Indiana University Health6 papers (2013–2022)Paul D. Brown · Radiation Oncology Associates6 papers (2012–2020)Nikhil Wagle · Gene Therapy Laboratory6 papers (2015–2024)Martin J. van den Bent · St James's University Hospital6 papers (2013–2020)Melissa E. Hughes · Yale Cancer Center6 papers (2012–2024)Janet Dancey · Queen's University6 papers (2013–2017)Lisa A. Carey · University of North Carolina at Chapel Hill5 papers (2014–2024)Sara M. Tolaney · Medidata (United States)5 papers (2020–2024)Riccardo Soffietti · European Institute of Oncology5 papers (2013–2019)Minesh P. Mehta · Carbon Engineering (Canada)5 papers (2012–2017)Elisabeth G.E. de Vries · Amsterdam Neuroscience4 papers (2016–2017)Romualdo Barroso‐Sousa · Universidade de Brasília4 papers (2020–2024)