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Romualdo Barroso‐Sousa

Universidade de Brasília · BR
Area of research
Oncology · Cancer Research
Research interest
Research interests include Cancer Immunotherapy and Biomarkers, Advanced Breast Cancer Therapies, Cancer Genomics and Diagnostics, and Breast Cancer Treatment Studies.
h-index
34
citations
6,651
works
253
NIH funding
primary concept
Medicine
email

Recent publications

Trastuzumab Deruxtecan plus Pertuzumab for HER2-Positive Metastatic Breast Cancer
New England Journal of Medicine 2025cited by 30position: middledoi
Trastuzumab deruxtecan (T-DXd) + pertuzumab (P) vs taxane + trastuzumab + pertuzumab (THP) for first-line (1L) treatment of patients (pts) with human epidermal growth factor receptor 2–positive (HER2+) advanced/metastatic breast cancer (a/mBC): Interim results from DESTINY-Breast09.
Journal of Clinical Oncology 2025cited by 27position: middledoi
LBA18 Trastuzumab deruxtecan (T-DXd) + pertuzumab (P) vs taxane + trastuzumab + pertuzumab (THP) for patients (pts) with HER2+ advanced/metastatic breast cancer (a/mBC): Additional analyses of DESTINY-Breast09 in key subgroups of interest
Annals of Oncology 2025cited by 3position: middledoi
Adjuvant Trastuzumab Emtansine Versus Paclitaxel Plus Trastuzumab for Stage I Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer: 5-Year Results and Correlative Analyses From ATEMPT
Journal of Clinical Oncology 2024cited by 36position: middledoi
Exemestane plus everolimus and palbociclib in metastatic breast cancer: clinical response and genomic/transcriptomic determinants of resistance in a phase I/II trial
Nature Communications 2024cited by 26position: middledoi
Adjuvant paclitaxel and trastuzumab for node-negative, HER2-positive breast cancer: final 10-year analysis of the open-label, single-arm, phase 2 APT trial
The Lancet Oncology 2023cited by 161position: middledoi
Comprehensive genomic characterization of HER2-low and HER2-0 breast cancer
Nature Communications 2023cited by 59position: middledoi
Quiescent cancer cells resist T cell attack by forming an immunosuppressive niche
Cell 2022cited by 313position: middledoi
Cardiac outcomes of subjects on adjuvant trastuzumab emtansine vs paclitaxel in combination with trastuzumab for stage I HER2-positive breast cancer (ATEMPT) study (TBCRC033): a randomized controlled trial
npj Breast Cancer 2022cited by 15position: firstdoi
Molecular correlates of response to eribulin and pembrolizumab in hormone receptor-positive metastatic breast cancer
Nature Communications 2021cited by 47position: middledoi
Prevalence and mutational determinants of high tumor mutation burden in breast cancer
Annals of Oncology 2020cited by 356position: firstdoi
Tumor Mutational Burden and <i>PTEN</i> Alterations as Molecular Correlates of Response to PD-1/L1 Blockade in Metastatic Triple-Negative Breast Cancer
Clinical Cancer Research 2020cited by 184position: firstdoi
Phase 2 study of buparlisib (BKM120), a pan-class I PI3K inhibitor, in patients with metastatic triple-negative breast cancer
Breast Cancer Research 2020cited by 145position: middledoi
The Impact of High-Dose Glucocorticoids on the Outcome of Immune-Checkpoint Inhibitor–Related Thyroid Disorders
Cancer Immunology Research 2019cited by 69position: middledoi
Endocrine Toxicity of Cancer Immunotherapy Targeting Immune Checkpoints
Endocrine Reviews 2018cited by 509position: middledoi
Incidence of Endocrine Dysfunction Following the Use of Different Immune Checkpoint Inhibitor Regimens
JAMA Oncology 2017cited by 1,070position: firstdoi
Wnt/beta-catenin pathway: modulating anticancer immune response
Journal of Hematology & Oncology 2017cited by 716position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Sara M. Tolaney · Medidata (United States)8 papers (2017–2025)F. Stephen Hodi · Harvard University4 papers (2017–2020)Nancy U. Lin · San Francisco Art Institute4 papers (2020–2024) · 3 papers (2017–2019)Esha Jain · University of Georgia3 papers (2020–2024)Ana C. Garrido-Castro · Harvard University3 papers (2017–2020)Ian E. Krop · Cancer Institute (WIA)3 papers (2017–2020)Nikhil Wagle · Gene Therapy Laboratory3 papers (2020–2024)Eric P. Winer · Yale University3 papers (2020–2020)Mothaffar F. Rimawi · Baylor College of Medicine2 papers (2025–2025) · 2 papers (2025–2025)Zefei Jiang · University of Sydney2 papers (2025–2025)Cristina Saura · Fudan University Shanghai Cancer Center2 papers (2020–2025) · 2 papers (2018–2019)Sibylle Loibl · Breast Center2 papers (2025–2025)Andreas Schneeweiß · NSABP Foundation2 papers (2025–2025) · 2 papers (2025–2025)Masakazu Toi · Universal Scientific Education and Research Network2 papers (2025–2025)Jie Liu · Central South University2 papers (2025–2025)Qingyuan Zhang · The Seventh Affiliated Hospital of Sun Yat-sen University2 papers (2025–2025)