Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Genomics and Chromatin Dynamics, Cancer Genomics and Diagnostics, RNA Research and Splicing, and Single-cell and spatial transcriptomics.
Fibroblasts of disparate developmental origins harbor anatomically variant scarring potential
MorPhiC Consortium: towards functional characterization of all human genes
Enhancer activation from transposable elements in extrachromosomal DNA
Genetic elements promote retention of extrachromosomal DNA in cancer cells
Reconstructing the three-dimensional architecture of extrachromosomal DNA with ec3D
Xist ribonucleoproteins promote female sex-biased autoimmunity
Bidirectional epigenetic editing reveals hierarchies in gene regulation
3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma
Single-cell multiome of the human retina and deep learning nominate causal variants in complex eye diseases
ecDNA hubs drive cooperative intermolecular oncogene expression
EPEN-04. ONCOGENIC 3D TUMOR GENOME ORGANIZATION IDENTIFIES NEW THERAPEUTIC TARGETS IN EPENDYMOMA
Oncogenic 3D genome conformations identify novel therapeutic targets in ependymoma
GENE-02. CHROMOSOME CONFORMATION ANALYSIS OF EPENDYMOMA IDENTIFIES PUTATIVE TUMOR DEPENDENCY GENES ACTIVATED BY DISTAL ONCOGENIC ENHANCERS
Identifying cis Elements for Spatiotemporal Control of Mammalian DNA Replication
Schaaf‐Yang syndrome overview: Report of 78 individuals
Identification of <i>cis</i> Elements for Spatio-temporal Control of DNA Replication
Identification of <i>cis</i> elements for spatio-temporal control of DNA replication
Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions