Area of research
Virology · Infectious Diseases
Research interest
Research interests include HIV Research and Treatment, SARS-CoV-2 and COVID-19 Research, Monoclonal and Polyclonal Antibodies Research, and Immunotherapy and Immune Responses.
Rapidly acquired HIV-1 neutralization breadth in a rhesus V2 apex knockin mouse model after a single bolus immunization.
Vaccination with an mRNA-encoded membrane-bound HIV envelope trimer induces neutralizing antibodies in animal models
mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodies
Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates
Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site
A combined adjuvant approach primes robust germinal center responses and humoral immunity in non-human primates
Author Correction: Long-primed germinal centres with enduring affinity maturation and clonal migration
Site of vulnerability on SARS-CoV-2 spike induces broadly protective antibody against antigenically distinct Omicron subvariants
Bispecific antibodies combine breadth, potency, and avidity of parental antibodies to neutralize sarbecoviruses
Long-primed germinal centres with enduring affinity maturation and clonal migration
A public antibody class recognizes an S2 epitope exposed on open conformations of SARS-CoV-2 spike
Targeted isolation of diverse human protective broadly neutralizing antibodies against SARS-like viruses
Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques
Cross-reactive serum and memory B-cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection
Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern
Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects
Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability
SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2
Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity
An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain
Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates
A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses
Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence
Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability
Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike
Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization
Structural basis for antibody recognition of the NANP repeats in <i>Plasmodium falciparum</i> circumsporozoite protein
Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP Trimers
Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies
Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes