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Jefferson Chan

University of Illinois Urbana-Champaign · US
Area of research
Biomedical Engineering · Molecular Biology
Research interest
Research interests include Nanoplatforms for cancer theranostics, Photoacoustic and Ultrasonic Imaging, Photodynamic Therapy Research Studies, and Genomics, phytochemicals, and oxidative stress.
h-index
55
citations
11,355
works
145
NIH funding
primary concept
email

Recent publications

Neutrophils exposed to a cholesterol metabolite secrete extracellular vesicles that promote epithelial-mesenchymal transition and stemness in breast cancer cells
Cancer Letters 2025cited by 4position: middledoi
A Conformationally Restricted Aza-BODIPY Platform for Stimulus-Responsive Probes with Enhanced Photoacoustic Properties
Journal of the American Chemical Society 2019cited by 135position: lastdoi
Copper regulates cyclic-AMP-dependent lipolysis
Nature Chemical Biology 2016cited by 214position: middledoi
Increased Energy Expenditure, Ucp1 Expression, and Resistance to Diet-induced Obesity in Mice Lacking Nuclear Factor-Erythroid-2-related Transcription Factor-2 (Nrf2)
Journal of Biological Chemistry 2016cited by 77position: lastdoi
Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids
Stem Cell Reports 2015cited by 115position: middledoi
Wilson Disease Protein ATP7B Utilizes Lysosomal Exocytosis to Maintain Copper Homeostasis
Developmental Cell 2014cited by 281position: middledoi
Copper is an endogenous modulator of neural circuit spontaneous activity
Proceedings of the National Academy of Sciences 2014cited by 149position: middledoi
Peptidoglycan Recognition Proteins Kill Bacteria by Inducing Oxidative, Thiol, and Metal Stress
PLoS Pathogens 2014cited by 95position: middledoi
Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts
Free Radical Biology and Medicine 2014cited by 93position: middledoi
Copper transporter 2 regulates intracellular copper and sensitivity to cisplatin
Metallomics 2014cited by 62position: middledoi
Molecular Imaging of Labile Iron(II) Pools in Living Cells with a Turn-On Fluorescent Probe
Journal of the American Chemical Society 2013cited by 175position: middledoi
Reaction-based small-molecule fluorescent probes for chemoselective bioimaging
Nature Chemistry 2012cited by 1,870position: firstdoi

Grants

CAREER: Photoacoustic Imaging Probes to Study the Biology of Metal Ions
NSF1752879$625,0002018–2023PIRePORTER

Frequent collaborators

Christopher J. Chang · Princeton University7 papers (2012–2016)Allegra T. Aron · University of Denver2 papers (2014–2016)Sheel C. Dodani · The University of Texas at Dallas2 papers (2012–2014)Pasquale Piccolo · University of Lausanne1 papers (2014–2014)Meritxell Huch · William Harvey Research Institute1 papers (2015–2015)Cheri M. Ackerman · Broad Institute1 papers (2016–2016)Andrea Ballabio · Baylor College of Medicine1 papers (2014–2014)Guy C. M. Grinwis · Utrecht University1 papers (2015–2015)Samouil L. Farhi · Broad Institute1 papers (2016–2016)Svetlana Lutsenko · Oregon Health & Science University1 papers (2016–2016)Lukas P. Smaga · University of California, Berkeley1 papers (2016–2016)Stephanie M. Cologna · University of Illinois Chicago1 papers (2025–2025) · 1 papers (2014–2014)Timothy Guan · University of California, Berkeley1 papers (2016–2016) · 1 papers (2014–2014)Mariama Fofana · Institute of Cancer Research1 papers (2014–2014) · 1 papers (2014–2014)Iztok Hozo · Indiana University1 papers (2014–2014)Theodore W. Kurtz · University of California, San Francisco1 papers (2016–2016)Lara Kockaya · University of Illinois Urbana-Champaign1 papers (2025–2025)