Area of research
Oncology · Immunology
Research interest
Research interests include Cancer Immunotherapy and Biomarkers, Immune cells in cancer, Epigenetics and DNA Methylation, and Cancer Genomics and Diagnostics.
A RAS(ON) Multi-Selective Inhibitor Combination Therapy Triggers Long-term Tumor Control through Senescence-Associated Tumor-Immune Equilibrium in Pancreatic Ductal Adenocarcinoma
SMAD4 induces opposite effects on metastatic growth from pancreatic tumors depending on the organ of residence
EZH2 inhibition remodels the inflammatory senescence-associated secretory phenotype to potentiate pancreatic cancer immune surveillance
Generation of precision preclinical cancer models using regulated in vivo base editing
Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants
MACHETE identifies interferon-encompassing chromosome 9p21.3 deletions as mediators of immune evasion and metastasis
Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer
Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer
Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer
Non-Cell-Autonomous Tumor Suppression by p53
Granule exocytosis mediates immune surveillance of senescent cells
A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions