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Alexander Stein

Hamburg Institut (Germany) · DE
Area of research
Oncology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Colorectal Cancer Treatments and Studies, Gastric Cancer Management and Outcomes, Cancer Immunotherapy and Biomarkers, and Colorectal Cancer Surgical Treatments.
h-index
38
citations
7,864
works
340
NIH funding
primary concept
Medicine
email

Recent publications

Differential effects of prior versus concomitant Steroid and Antibiotic Treatment on Immunotherapy Efficacy - A Pooled Analysis of the RAMONA, INTEGA, OPTIM, ELDORANDO, FORCE, TITAN-RCC and TITAN-TCC Trials of the German AIO Study Group.
2026cited by 0position: contributordoi
Fruquintinib in combination with tislelizumab versus trifluridine/tipiracil and bevacizumab in third-line and beyond MSS mCRC without active liver metastases—the IKF-080/AIO-QUINTIS trial
ESMO Gastrointestinal Oncology 2026cited by 0position: contributordoi
Perioperative Durvalumab in Gastric and Gastroesophageal Junction Cancer
New England Journal of Medicine 2025cited by 197position: middledoi
Zanzalintinib plus atezolizumab versus regorafenib in refractory colorectal cancer (STELLAR-303): a randomised, open-label, phase 3 trial
The Lancet 2025cited by 18position: middledoi
Inflammation and limited adaptive immunity predict worse outcomes on immunotherapy in head and neck cancer
npj Precision Oncology 2025cited by 7position: middledoi
UV1 vaccination in pembrolizumab-treated patients with recurrent or metastatic head and neck cancer: A randomized multicenter phase 2 trial
Med 2025cited by 6position: middledoi
Inflammatory Stress Determines the Need for Chemotherapy in Patients with HER2-Positive Esophagogastric Adenocarcinoma Receiving Targeted Therapy and Immunotherapy.
2025cited by 4position: contributordoi
Author Correction: Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer
Nature 2025cited by 2position: middledoi
FOLFOXIRI/bevacizumab versus doublets/bevacizumab as initial therapy of unresectable liver-only, right-sided and/or RAS or BRAF mutated metastatic colorectal cancer: An individual patient data-based pooled analysis of randomized trials
European Journal of Cancer 2025cited by 2position: middledoi
Perioperative pembrolizumab, trastuzumab and FLOT in HER2-positive localized esophagogastric adenocarcinoma: a phase 2 trial.
2025cited by 2position: contributordoi
FOLFOXIRI/bevacizumab versus doublets/bevacizumab as initial therapy of unresectable liver-only, right-sided and/or RAS or BRAF mutated metastatic colorectal cancer: An individual patient data-based pooled analysis of randomized trials
European Journal of Cancer 2025cited by 1position: contributordoi
Data from Inflammatory Stress Determines the Need for Chemotherapy in Patients with HER2-Positive Esophagogastric Adenocarcinoma Receiving Targeted Therapy and Immunotherapy
2025cited by 0position: contributordoi
Supplementary Figure 1 from Inflammatory Stress Determines the Need for Chemotherapy in Patients with HER2-Positive Esophagogastric Adenocarcinoma Receiving Targeted Therapy and Immunotherapy
2025cited by 0position: contributordoi
Supplementary Tables 1-3 from Inflammatory Stress Determines the Need for Chemotherapy in Patients with HER2-Positive Esophagogastric Adenocarcinoma Receiving Targeted Therapy and Immunotherapy
2025cited by 0position: contributordoi
Supplementary Figure 4 from Inflammatory Stress Determines the Need for Chemotherapy in Patients with HER2-Positive Esophagogastric Adenocarcinoma Receiving Targeted Therapy and Immunotherapy
2025cited by 0position: contributordoi
Supplementary Figure 3 from Inflammatory Stress Determines the Need for Chemotherapy in Patients with HER2-Positive Esophagogastric Adenocarcinoma Receiving Targeted Therapy and Immunotherapy
2025cited by 0position: contributordoi
Supplementary Figure 2 from Inflammatory Stress Determines the Need for Chemotherapy in Patients with HER2-Positive Esophagogastric Adenocarcinoma Receiving Targeted Therapy and Immunotherapy
2025cited by 0position: contributordoi
A Multimodal Lifestyle Psychosocial Survivorship Program in Young Cancer Survivors
JAMA Network Open 2024cited by 15position: middledoi
Tolerability and efficacy of the cancer vaccine UV1 in patients with recurrent or metastatic PD-L1 positive head and neck squamous cell carcinoma planned for first-line treatment with pembrolizumab – the randomized phase 2 FOCUS trial
Frontiers in Oncology 2024cited by 11position: middledoi
Trametinib in combination with hydroxychloroquine or palbociclib in advanced metastatic pancreatic cancer: data from a retrospective, multicentric cohort (AIO AIO-TF/PAK-0123)
Journal of Cancer Research and Clinical Oncology 2024cited by 10position: middledoi
Safety of preventive HIPEC in combination with perioperative FLOT versus FLOT alone for resectable diffuse type gastric and gastroesophageal junction type II/III adenocarcinoma: An interim safety analysis from the phase III PREVENT trial of the AIO/CAOGI/ACO.
Journal of Clinical Oncology 2024cited by 2position: middledoi
FOLFOXIRI/bevacizumab (bev) versus doublets/bev as initial therapy of unresectable liver-only, right-sided and/or <i>RAS</i> or <i>BRAF</i> mutated (mut) metastatic colorectal cancer (mCRC): An individual patient data-based pooled analysis of randomized trials.
Journal of Clinical Oncology 2024cited by 0position: middledoi
Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer
Nature 2023cited by 444position: middledoi
Dabrafenib plus trametinib in BRAFV600E-mutated rare cancers: the phase 2 ROAR trial
Nature Medicine 2023cited by 287position: middledoi
Dabrafenib plus trametinib in patients with relapsed/refractory BRAF V600E mutation-positive hairy cell leukemia.
2023cited by 36position: contributordoi
Pembrolizumab and trastuzumab in combination with FLOT in the perioperative treatment of HER2-positive, localized esophagogastric adenocarcinoma—a phase II trial of the AIO study group (AIO STO 0321)
Frontiers in Oncology 2023cited by 8position: middledoi
A post hoc analysis of the EPAZ trial: The role of geriatric variables in elderly soft tissue sarcoma patients on toxicity and outcome.
2023cited by 2position: contributordoi
Dabrafenib plus trametinib in patients with BRAF<sup>V600E</sup>-mutant low-grade and high-grade glioma (ROAR): a multicentre, open-label, single-arm, phase 2, basket trial.
2022cited by 274position: contributordoi
Efficacy of Ipilimumab vs FOLFOX in Combination With Nivolumab and Trastuzumab in Patients With Previously Untreated ERBB2-Positive Esophagogastric Adenocarcinoma: The AIO INTEGA Randomized Clinical Trial.
2022cited by 61position: contributordoi
Dose-escalation and dose-expansion study of trastuzumab deruxtecan (T-DXd) monotherapy and combinations in patients (pts) with advanced/metastatic HER2+ gastric cancer (GC)/gastroesophageal junction adenocarcinoma (GEJA): DESTINY-Gastric03.
Journal of Clinical Oncology 2022cited by 42position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

· 13 papers (2020–2026)Ralf‐Dieter Hofheinz · Heidelberg University5 papers (2013–2023)Hans‐Joachim Schmoll · University Hospital in Halle4 papers (2013–2025)Thomas J. Ettrich · Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie4 papers (2020–2025)Mascha Binder · University of Freiburg4 papers (2023–2025)Peter Thuss‐Patience · Universität Hamburg4 papers (2013–2022)Axel Hinke · Hochschule Düsseldorf University of Applied Sciences4 papers (2021–2025) · 3 papers (2024–2025) · 3 papers (2018–2020)Mascha Binder · Biologie Labor3 papers (2020–2025)Joseph Tintelnot · Universität Hamburg3 papers (2025–2026)Jan H.M. Schellens · University of Applied Sciences Utrecht3 papers (2019–2023)Viktor Grünwald · Dana-Farber Cancer Institute3 papers (2019–2020)Aislyn Boran · Daiichi Sankyo (United States)3 papers (2019–2023)Palanichamy Ilankumaran · Center for Global Development3 papers (2019–2023)Zev A. Wainberg · UCLA Medical Center3 papers (2019–2023)Jenny Chang‐Claude · Centre hospitalier universitaire de Québec3 papers (2018–2020)Patrick Y. Wen · Harvard University3 papers (2019–2023)Élena Elez · Comprehensive Cancer Center Vienna3 papers (2019–2023)Vivek Subbiah · International Drug Development3 papers (2019–2023)