Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Cancer-related molecular mechanisms research, RNA modifications and cancer, MicroRNA in disease regulation, and Circular RNAs in diseases.
New insight into circRNAs: characterization, strategies, and biomedical applications
METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m6A homeostasis
Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex
The snoRNA-like lncRNA LNC-SNO49AB drives leukemia by activating the RNA-editing enzyme ADAR1
MiRNA-148a inhibits cell growth and drug resistance by regulating WNT10a expression in renal cell carcinoma
The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation
The m6A writers regulated by the IL-6/STAT3 inflammatory pathway facilitate cancer cell stemness in cholangiocarcinoma
Polysome profiling followed by quantitative PCR for identifying potential micropeptide encoding long non-coding RNAs in suspension cell lines
The lncRNA LAMP5-AS1 drives leukemia cell stemness by directly modulating DOT1L methyltransferase activity in MLL leukemia
circMYBL2, a circRNA from MYBL2, regulates FLT3 translation by recruiting PTBP1 to promote FLT3-ITD AML progression
Noncoding RNAs in cancer therapy resistance and targeted drug development
circRNA circAF4 functions as an oncogene to regulate MLL-AF4 fusion protein expression and inhibit MLL leukemia progression
LncRNA ANRIL regulates AML development through modulating the glucose metabolism pathway of AdipoR1/AMPK/SIRT1
MIR-708 promotes phagocytosis to eradicate T-ALL cells by targeting CD47
Caspase‑10, matrix metalloproteinase‑9 and total laminin are correlated with the tumor malignancy of clear cell renal cell carcinoma
Increased expression of GGN promotes tumorigenesis in bladder cancer and is correlated with poor prognosis
The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway
LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner
Identification of biological targets of therapeutic intervention for clear cell renal cell carcinoma based on bioinformatics approach
Circulating miRNAs in cancer: from detection to therapy
miR-133b, a muscle-specific microRNA, is a novel prognostic marker that participates in the progression of human colorectal cancer via regulation of CXCR4 expression
Circulating MicroRNAs Identified in a Genome-Wide Serum MicroRNA Expression Analysis as Noninvasive Biomarkers for Endometriosis