Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Cancer-related molecular mechanisms research, MicroRNA in disease regulation, RNA modifications and cancer, and RNA Research and Splicing.
Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex
The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation
Polysome profiling followed by quantitative PCR for identifying potential micropeptide encoding long non-coding RNAs in suspension cell lines
The lncRNA LAMP5-AS1 drives leukemia cell stemness by directly modulating DOT1L methyltransferase activity in MLL leukemia
circMYBL2, a circRNA from MYBL2, regulates FLT3 translation by recruiting PTBP1 to promote FLT3-ITD AML progression
Noncoding RNAs in cancer therapy resistance and targeted drug development
circRNA circAF4 functions as an oncogene to regulate MLL-AF4 fusion protein expression and inhibit MLL leukemia progression
LncRNA ANRIL regulates AML development through modulating the glucose metabolism pathway of AdipoR1/AMPK/SIRT1
MIR-708 promotes phagocytosis to eradicate T-ALL cells by targeting CD47