Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Cancer-related molecular mechanisms research, RNA modifications and cancer, RNA Research and Splicing, and Circular RNAs in diseases.
IBR1, a novel endogenous IFIH1-binding dsRNA, governs IFIH1 activation and M1 macrophage polarisation in ARDS.
Uric acid, high density lipoprotein cholesterol levels and their ratio are related to microbial enterotypes and serum metabolites in females with a blood stasis constitution
METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m6A homeostasis
METTL3 protects METTL14 from STUB1-mediated degradation to maintain m<sup>6</sup> A homeostasis.
Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex
The snoRNA-like lncRNA LNC-SNO49AB drives leukemia by activating the RNA-editing enzyme ADAR1
The snoRNA-like lncRNA LNC-SNO49AB drives leukemia by activating the RNA-editing enzyme ADAR1.
N6-methyladenosine methyltransferases: functions, regulation, and clinical potential
N6-methyladenosine methyltransferases: functions, regulation, and clinical potential.
The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation
Myofibroblast‐Specific Msi2 Knockout Inhibits HCC Progression in a Mouse Model
A CRISPR/CAS9-based strategy targets the personalized chimeric neosequence in fusion-driven cancer genome for precision medicine.
The lncRNA LAMP5-AS1 drives leukemia cell stemness by directly modulating DOT1L methyltransferase activity in MLL leukemia
Cis-acting lnc-eRNA SEELA directly binds histone H4 to promote histone recognition and leukemia progression.
circMYBL2, a circRNA from MYBL2, regulates FLT3 translation by recruiting PTBP1 to promote FLT3-ITD AML progression
circRNA circAF4 functions as an oncogene to regulate MLL-AF4 fusion protein expression and inhibit MLL leukemia progression
circRNA circAF4 functions as an oncogene to regulate MLL-AF4 fusion protein expression and inhibit MLL leukemia progression.
LncRNA ANRIL regulates AML development through modulating the glucose metabolism pathway of AdipoR1/AMPK/SIRT1
MIR-708 promotes phagocytosis to eradicate T-ALL cells by targeting CD47
A simple in vitro tumor chemosensitivity assay based on cell penetrating peptide tagged luciferase
The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway
Formation and determination of the oxidation products of 5-methylcytosine in RNA
Long non-coding RNA NKILA inhibits migration and invasion of tongue squamous cell carcinoma cells via suppressing epithelial-mesenchymal transition
Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein
Determination of DNA adenine methylation in genomes of mammals and plants by liquid chromatography/mass spectrometry
Mitochondrial fission determines cisplatin sensitivity in tongue squamous cell carcinoma through the BRCA1-miR-593-5p–MFF axis