Area of research
Epidemiology · Infectious Diseases
Research interest
Research interests include Influenza Virus Research Studies, SARS-CoV-2 and COVID-19 Research, RNA and protein synthesis mechanisms, and Viral Infections and Immunology Research.
AI-Driven Antimicrobial Peptide Discovery: Mining and Generation
Naturally Occurring Mutations of SARS-CoV-2 Main Protease Confer Drug Resistance to Nirmatrelvir
A yeast-based system to study SARS-CoV-2 Mpro structure and to identify nirmatrelvir resistant mutations
Structure-based design of SARS-CoV-2 papain-like protease inhibitors
Additional file 3 of Transcriptome analysis of barley (Hordeum vulgare L.) under waterlogging stress, and overexpression of the HvADH4 gene confers waterlogging tolerance in transgenic Arabidopsis
Additional file 1 of Transcriptome analysis of barley (Hordeum vulgare L.) under waterlogging stress, and overexpression of the HvADH4 gene confers waterlogging tolerance in transgenic Arabidopsis
Additional file 2 of Transcriptome analysis of barley (Hordeum vulgare L.) under waterlogging stress, and overexpression of the HvADH4 gene confers waterlogging tolerance in transgenic Arabidopsis
Additional file 5 of Transcriptome analysis of barley (Hordeum vulgare L.) under waterlogging stress, and overexpression of the HvADH4 gene confers waterlogging tolerance in transgenic Arabidopsis
Validation and Invalidation of SARS-CoV-2 Papain-like Protease Inhibitors
Brilacidin, a COVID‐19 drug candidate, demonstrates broad‐spectrum antiviral activity against human coronaviruses OC43, 229E, and NL63 through targeting both the virus and the host cell
Point-of-care SARS-CoV-2 sensing using lens-free imaging and a deep learning-assisted quantitative agglutination assay
A unique class of Zn2+-binding serine-based PBPs underlies cephalosporin resistance and sporogenesis in Clostridioides difficile
Drug-Repurposing Screening Identified Tropifexor as a SARS-CoV-2 Papain-like Protease Inhibitor
Cytopathic Effect Assay and Plaque Assay to Evaluate in vitro Activity of Antiviral Compounds Against Human Coronaviruses 229E, OC43, and NL63
Invalidation of dieckol and 1,2,3,4,6-pentagalloylglucose (PGG) as SARS-CoV-2 main protease inhibitors and the discovery of PGG as a papain-like protease inhibitor
Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19
Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay
The <i>in vitro</i> antiviral activity of lactoferrin against common human coronaviruses and SARS-CoV-2 is mediated by targeting the heparan sulfate co-receptor
Expedited Approach toward the Rational Design of Noncovalent SARS-CoV-2 Main Protease Inhibitors
Discovery of Di- and Trihaloacetamides as Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity
Boceprevir, Calpain Inhibitors II and XII, and GC-376 Have Broad-Spectrum Antiviral Activity against Coronaviruses
Rational Design of Hybrid SARS-CoV-2 Main Protease Inhibitors Guided by the Superimposed Cocrystal Structures with the Peptidomimetic Inhibitors GC-376, Telaprevir, and Boceprevir
Enterovirus A71 antivirals: Past, present, and future
Validation and invalidation of SARS-CoV-2 main protease inhibitors using the Flip-GFP and Protease-Glo luciferase assays
Efficacy of GC-376 against SARS-CoV-2 virus infection in the K18 hACE2 transgenic mouse model
Dipyridamole, chloroquine, montelukast sodium, candesartan, oxytetracycline, and atazanavir are not SARS-CoV-2 main protease inhibitors
Enhanced mucosal penetration and efficient inhibition efficacy against cervical cancer of PEGylated docetaxel nanocrystals by TAT modification
Discovery of Potent and Broad-Spectrum Pyrazolopyridine-Containing Antivirals against Enteroviruses D68, A71, and Coxsackievirus B3 by Targeting the Viral 2C Protein
Influenza AM2 Channel Oligomerization Is Sensitive to Its Chemical Environment
The synergistic antifungal activity of resveratrol with azoles against <i>Candida albicans</i>
CSR: Small: Cross-Layer Scheduling to Democratize AI for Foundation Model Inference Serving - An Algorithm-System Co-design Approach
RII FEC: Data-Advanced Research and Education to Improve Weather Intelligence and Localized Climate Change Assessment and Resilience in Agriculture-based Communities
CAREER: Leveraging Virtual Reality (VR) and Artificial Intelligence (AI) to Maximize Skill Transfer in Human-Robot Interaction and Collaboration (HRI/C) for Advanced Construction
SHF: Small: Taming Huge Page Problems for Memory Bulk Operations Using a Hardware/Software Co-Design Approach
Collaborative Research: CIF: Medium: An Algorithmic Theory of Hamiltonian Dynamics for Sampling, Optimization, and Games
CDS&E/Collaborative Research: Data-Driven Inverse Design of Additively Manufacturable Aperiodic Architected Cellular Materials
PPoSS: Planning: Data Centric Computing for Scalable Heterogeneous Memory and Storage Systems Architecture
SHF: Small: Revamping I/O Architectures Using Machine Learning Techniques on Big Compute Machines
SHF: Small: Developing a Highly Efficient and Accurate Approximation System for Warehouse-Scale Computers with the Sub-dataset Distribution Aware Approach
SHF: Small: Multi-criteria optimization control for temperature constrained energy efficient data center using fuzzy decision making theory
XPS: SDA: Collaborative Research: A Scalable and Distributed System Framework for Compute-Intensive and Data-Parallel Applications
CSR: Small: DSA-Cloud: Data Semantics Aware Clouds for High Performance Analytics
SOCS: Socially Intelligent Computing to Support Citizen Science
CAREER: Data-Intensive HPC Analytics: A Systems Approach Through Extended Interfaces, Data Restructuring and Data-centric Scheduling
CPA-ACR: Fast Recovery Using Optimal and Near-Optimal Parallelism in Data-Intensive Computing
CSR-PDOS: Energy-Efficient, High-Performance Storage Array Systems
Collaborative: CSR-PDOS: Energy Conservation in Storage Systems using Coding Techniques
Collaborative: CSR-PDOS: Energy Conservation in Storage Systems using Coding Techniques
CSR-PDOS: Energy-Efficient, High-Performance Storage Array Systems
An I/O Buffer Cache Architecture for Remote Direct Memory Access