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Dale C. Guenther

University of Idaho · US
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Area of research
Molecular Biology
Research interest
Research focused on DNA and Oligonucleotide, with related work in Nucleic acid, Computational biology, Sequence (biology). Notable publications include 'Chimeric siRNAs with chemically modified pentofuranose and hexopyranose nucleotides: altritol-nucleotide (ANA) containing GalNAc–siRNA conjugates: in vitro and in vivo RNAi...', 'Synthesis and Biophysical Properties of C5-Functionalized LNA (Locked Nucleic Acid)', and 'Identification and Characterization of Second-Generation Invader Locked Nucleic Acids (LNAs) for Mixed-Sequence Recognition of Double-Stranded DNA'.
h-index
citations
307
works
17
NIH funding
primary concept
email

Recent publications

Recognition of double-stranded DNA using LNA-modified toehold Invader probes
Organic & Biomolecular Chemistry 2021cited by 9position: middledoi
Chimeric siRNAs with chemically modified pentofuranose and hexopyranose nucleotides: altritol-nucleotide (ANA) containing GalNAc–siRNA conjugates: in vitro and in vivo RNAi activity and resistance to 5′-exonuclease
Nucleic Acids Research 2020cited by 43position: middledoi
Impact of non-nucleotidic bulges on recognition of mixed-sequence dsDNA by pyrene-functionalized Invader probes
Organic & Biomolecular Chemistry 2020cited by 1position: firstdoi
Head-to-head comparison of LNA, <sup>MP</sup>γPNA, INA and Invader probes targeting mixed-sequence double-stranded DNA
Organic & Biomolecular Chemistry 2019cited by 18position: middledoi
Synthesis and biophysical characterization of oligonucleotides modified with O2′-alkylated RNA monomers featuring substituted pyrene moieties
Organic & Biomolecular Chemistry 2018cited by 4position: middledoi
Recognition of mixed-sequence DNA using double-stranded probes with interstrand zipper arrangements of O2′-triphenylene- and coronene-functionalized RNA monomers
Organic & Biomolecular Chemistry 2017cited by 6position: middledoi
Invader probes: harnessing the energy of intercalation to facilitate recognition of chromosomal DNA for diagnostic applications
Chemical Science 2015cited by 29position: firstdoi
Bulged Invader probes: activated duplexes for mixed-sequence dsDNA recognition with improved thermodynamic and kinetic profiles
Chemical Communications 2015cited by 18position: firstdoi
Synthesis and Biophysical Properties of C5-Functionalized LNA (Locked Nucleic Acid)
The Journal of Organic Chemistry 2014cited by 32position: middledoi
Recognition of double-stranded DNA using energetically activated duplexes with interstrand zippers of 1-, 2- or 4-pyrenyl-functionalized <i>O</i>2′-alkylated RNA monomers
Organic & Biomolecular Chemistry 2014cited by 25position: middledoi
Carbohydrate-Functionalized Locked Nucleic Acids: Oligonucleotides with Extraordinary Binding Affinity, Target Specificity, and Enzymatic Stability
Organic Letters 2014cited by 13position: middledoi
C5-Amino acid functionalized LNA: positively poised for antisense applications
Chemical Communications 2014cited by 12position: firstdoi
C5-Alkynyl-Functionalized α-L-LNA: Synthesis, Thermal Denaturation Experiments and Enzymatic Stability
The Journal of Organic Chemistry 2014cited by 8position: middledoi
Identification and Characterization of Second-Generation Invader Locked Nucleic Acids (LNAs) for Mixed-Sequence Recognition of Double-Stranded DNA
The Journal of Organic Chemistry 2013cited by 32position: middledoi
Sandwich assay for mixed-sequence recognition of double-stranded DNA: Invader-based detection of targets specific to foodborne pathogens
Chemical Communications 2013cited by 20position: middledoi
Recognition of Mixed-Sequence DNA Duplexes: Design Guidelines for Invaders Based on 2′-<i>O</i>-(Pyren-1-yl)methyl-RNA Monomers
The Journal of Organic Chemistry 2013cited by 19position: middledoi
Invaders: Recognition of Double‐Stranded DNA by Using Duplexes Modified with Interstrand Zippers of 2′‐<i>O</i>‐(Pyren‐1‐yl)methyl‐ribonucleotides
ChemBioChem 2013cited by 18position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Patrick J. Hrdlicka · University of Idaho16 papers (2013–2021)Saswata Karmakar · University of Idaho12 papers (2013–2021)Brooke A. Anderson · University of Idaho5 papers (2013–2015)Pawan Kumar · University of Idaho5 papers (2013–2020)Raymond G. Emehiser · University of Idaho3 papers (2018–2020)Bradley C. Gibbons · University of Idaho3 papers (2014–2018)Bharat Baral · University of Idaho2 papers (2014–2014)Sujay P. Sau · University of Idaho2 papers (2013–2013)Pawan K. Sharma · University of Idaho2 papers (2014–2014)Michael E. Østergaard · University of Idaho2 papers (2014–2014) · 2 papers (2013–2015) · 2 papers (2013–2014)Mamta Kaura · University of Idaho2 papers (2014–2014) · 2 papers (2013–2015) · 1 papers (2020–2020)Eric Hall · University of Idaho1 papers (2019–2019)Wei Guo · California Institute of Technology1 papers (2015–2015)Piet Herdewijn · KU Leuven1 papers (2020–2020)Mikhail Abramov · KU Leuven1 papers (2020–2020)Guy Schepers · KU Leuven1 papers (2020–2020)
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