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Leslie A. Lange

Johns Hopkins University · US
Area of research
Genetics · Molecular Biology
Research interest
Research interests include Genetic Associations and Epidemiology, Genetic Mapping and Diversity in Plants and Animals, Genomics and Rare Diseases, and RNA modifications and cancer.
h-index
53
citations
17,030
works
224
NIH funding
primary concept
Medicine
email

Recent publications

Epigenome-wide DNA methylation association study of CHIP provides insight into perturbed gene regulation
Nature Communications 2025cited by 6position: middledoi
Human plasma proteomic profile of clonal hematopoiesis
Nature Communications 2025cited by 2position: middledoi
X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements
Nature Communications 2024cited by 12position: middledoi
Polygenic Risk for Type 2 Diabetes in African Americans
Diabetes 2024cited by 8position: middledoi
Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification
Nature Genetics 2023cited by 147position: middledoi
Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease
Nature Communications 2023cited by 65position: middledoi
Clonal Hematopoiesis of Indeterminate Potential (CHIP) and Incident Type 2 Diabetes Risk
Diabetes Care 2023cited by 63position: middledoi
Mendelian randomization study of diabetes and dementia in the Million Veteran Program
Alzheimer s & Dementia 2023cited by 32position: middledoi
Genetic insights into resting heart rate and its role in cardiovascular disease
Nature Communications 2023cited by 31position: middledoi
Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification
Nature Cardiovascular Research 2023cited by 17position: middledoi
Large-scale genome-wide association study of coronary artery disease in genetically diverse populations
Nature Medicine 2022cited by 339position: middledoi
Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies
Kidney International 2022cited by 52position: middledoi
The Value of Rare Genetic Variation in the Prediction of Common Obesity in European Ancestry Populations
Frontiers in Endocrinology 2022cited by 20position: middledoi
A Diabetes Genetic Risk Score Is Associated With All-Cause Dementia and Clinically Diagnosed Vascular Dementia in the Million Veteran Program
Diabetes Care 2022cited by 18position: middledoi
The trans-ancestral genomic architecture of glycemic traits
Nature Genetics 2021cited by 878position: middledoi
Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation
Human Genetics 2021cited by 70position: middledoi
Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes
The American Journal of Human Genetics 2021cited by 70position: middledoi
Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program
The American Journal of Human Genetics 2021cited by 25position: middledoi
Obesity Partially Mediates the Diabetogenic Effect of Lowering LDL Cholesterol
Diabetes Care 2021cited by 24position: middledoi
Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations
Cell 2020cited by 726position: middledoi
Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline
Kidney International 2020cited by 98position: middledoi
Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke
Stroke 2020cited by 66position: middledoi
Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity
Diabetes 2020cited by 55position: middledoi
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria
Nature Communications 2019cited by 234position: middledoi
Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
Nature Genetics 2019cited by 32position: middledoi
Genome-Wide Association Study of Apparent Treatment-Resistant Hypertension in the CHARGE Consortium: The CHARGE Pharmacogenetics Working Group
American Journal of Hypertension 2019cited by 24position: middledoi
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
Nature Genetics 2018cited by 1,709position: middledoi
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
Nature Genetics 2018cited by 468position: middledoi
Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity
Nature Communications 2017cited by 176position: middledoi
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
bioRxiv (Cold Spring Harbor Laboratory) 2017cited by 0position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Marijana Vujković · Vanderbilt University Medical Center2 papers (2022–2023)Sridharan Raghavan · Johns Hopkins University2 papers (2022–2023)Mark W. Logue · Boston University2 papers (2022–2023) · 2 papers (2022–2023)Julie A. Lynch · University of Utah2 papers (2022–2023)Elizabeth Litkowski · University of Colorado Denver2 papers (2022–2023)Richard L. Hauger · Janssen (Belgium)2 papers (2022–2023)John E. Hokanson · University of Colorado Anschutz Medical Campus2 papers (2022–2023)Ethan M. Lange · Colorado School of Public Health2 papers (2022–2023)Lawrence S. Phillips · VA Tennessee Valley Healthcare System2 papers (2022–2023)Hemant K. Tiwari · Sikkim University1 papers (2024–2024)Maggie C. Y. Ng · Wake Forest University1 papers (2024–2024)Ruth J. F. Loos · Baylor Genetics1 papers (2024–2024)Tian Ge · Harvard University1 papers (2024–2024)Vinodh Srinivasasainagendra · University of Alabama at Birmingham1 papers (2024–2024)James B. Meigs · Harvard University1 papers (2024–2024)Lauren Stalbow · Rockefeller University1 papers (2024–2024)Jordan W. Smoller · Broad Institute1 papers (2024–2024)Eimear E. Kenny · Mount Sinai Hospital1 papers (2024–2024)Nicole D. Armstrong · AVEO Oncology (United States)1 papers (2024–2024)