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Ethan M. Lange

Colorado School of Public Health · US
Area of research
Genetics · Pulmonary and Respiratory Medicine
Research interest
Research interests include Genetic Associations and Epidemiology, Prostate Cancer Treatment and Research, Epigenetics and DNA Methylation, and Prostate Cancer Diagnosis and Treatment.
h-index
63
citations
20,722
works
365
NIH funding
primary concept
email

Recent publications

Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele
Nature Communications 2025cited by 5position: middledoi
Rare variant contribution to the heritability of coronary artery disease
Nature Communications 2024cited by 13position: middledoi
A methylation risk score for chronic kidney disease: a HyperGEN study
Scientific Reports 2024cited by 11position: middledoi
Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease
Nature Communications 2023cited by 65position: middledoi
Mendelian randomization study of diabetes and dementia in the Million Veteran Program
Alzheimer s & Dementia 2023cited by 32position: middledoi
Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas
Cell Genomics 2023cited by 19position: middledoi
Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data
Nature Genetics 2022cited by 354position: middledoi
Protein prediction for trait mapping in diverse populations
PLoS ONE 2022cited by 28position: middledoi
A Diabetes Genetic Risk Score Is Associated With All-Cause Dementia and Clinically Diagnosed Vascular Dementia in the Million Veteran Program
Diabetes Care 2022cited by 18position: middledoi
Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci
Genome Medicine 2021cited by 55position: middledoi
DNAm-based signatures of accelerated aging and mortality in blood are associated with low renal function
Clinical Epigenetics 2021cited by 37position: middledoi
Variant-specific inflation factors for assessing population stratification at the phenotypic variance level
Nature Communications 2021cited by 21position: middledoi
Genetic Contributors of Incident Stroke in 10,700 African Americans With Hypertension: A Meta-Analysis From the Genetics of Hypertension Associated Treatments and Reasons for Geographic and Racial Differences in Stroke Studies
Frontiers in Genetics 2021cited by 20position: middledoi
Coagulation factor VIII: Relationship to cardiovascular disease risk and whole genome sequence and epigenome‐wide analysis in African Americans
Journal of Thrombosis and Haemostasis 2020cited by 26position: middledoi
Interferon gamma-induced protein 10 (IP-10) and cardiovascular disease in African Americans
PLoS ONE 2020cited by 18position: middledoi
Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations
Nature Communications 2019cited by 101position: middledoi
REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants
The American Journal of Human Genetics 2016cited by 2,933position: middledoi
Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals
The American Journal of Human Genetics 2016cited by 99position: middledoi
Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits
The American Journal of Human Genetics 2016cited by 98position: middledoi
Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21
Human Genetics 2016cited by 44position: middledoi
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility
Nature Communications 2015cited by 201position: middledoi
Rare coding variants and X-linked loci associated with age at menarche
Nature Communications 2015cited by 46position: middledoi
Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction
Nature 2014cited by 677position: middledoi
Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol
The American Journal of Human Genetics 2014cited by 217position: middledoi
Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans
Human Genetics 2014cited by 38position: middledoi
Association analysis of 9,560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease
Human Genetics 2013cited by 32position: middledoi
Germline Mutations in <i>HOXB13</i> and Prostate-Cancer Risk
New England Journal of Medicine 2012cited by 667position: middledoi
HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG)
Human Genetics 2012cited by 198position: middledoi
Imputation of Exome Sequence Variants into Population- Based Samples and Blood-Cell-Trait-Associated Loci in African Americans: NHLBI GO Exome Sequencing Project
The American Journal of Human Genetics 2012cited by 151position: middledoi
Soluble CD14
Arteriosclerosis Thrombosis and Vascular Biology 2012cited by 148position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Alex P. Reiner · Brigham and Women's Hospital4 papers (2012–2020)Leslie A. Lange · University of North Carolina at Chapel Hill4 papers (2012–2020)Paul L. Auer · Medical College of Wisconsin3 papers (2012–2020)Mary Cushman · Kidney Research UK3 papers (2012–2020)Lawrence S. Phillips · VA Tennessee Valley Healthcare System2 papers (2022–2023)Marguerite R. Irvin · University of Alabama at Birmingham2 papers (2020–2021)Timothy A. Thornton · Regeneron (United States)2 papers (2020–2020)James G. Wilson · Beth Israel Deaconess Medical Center2 papers (2020–2020)Neil A. Zakai · University of Vermont2 papers (2020–2020)Leslie A. Lange · Johns Hopkins University2 papers (2022–2023)Marijana Vujković · Vanderbilt University Medical Center2 papers (2022–2023)Sridharan Raghavan · Johns Hopkins University2 papers (2022–2023)Mark W. Logue · Boston University2 papers (2022–2023) · 2 papers (2022–2023)Laura M. Raffield · University of North Carolina at Chapel Hill2 papers (2020–2020)Julie A. Lynch · University of Utah2 papers (2022–2023)Russell P. Tracy · University of Vermont2 papers (2012–2020)Elizabeth Litkowski · University of Colorado Denver2 papers (2022–2023)Richard L. Hauger · Janssen (Belgium)2 papers (2022–2023)John E. Hokanson · University of Colorado Anschutz Medical Campus2 papers (2022–2023)