Area of research
Pulmonary and Respiratory Medicine · Molecular Biology
Research interest
Research interests include Biology, Cancer research, Transcription factor, Chromatin, Enhancer, and Carcinogenesis.
p300/CBP is an essential driver of pathogenic enhancer activity and gene expression in Ewing sarcoma
DrugMap: A quantitative pan-cancer analysis of cysteine ligandability
The ETS transcription factor ETV6 constrains the transcriptional activity of EWS–FLI to promote Ewing sarcoma
Non-canonical integrin signaling activates EGFR and RAS-MAPK-ERK signaling in small cell lung cancer
Reverse Transcriptase Inhibition Disrupts Repeat Element Life Cycle in Colorectal Cancer
Diagnostic Value of MAML2 Rearrangements in Mucoepidermoid Carcinoma
Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma
Stromal Microenvironment Shapes the Intratumoral Architecture of Pancreatic Cancer
Resolving medulloblastoma cellular architecture by single-cell genomics
COX-2 mediates tumor-stromal prolactin signaling to initiate tumorigenesis
Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq
Cancer-Specific Retargeting of BAF Complexes by a Prion-like Domain
OTX2 Activity at Distal Regulatory Elements Shapes the Chromatin Landscape of Group 3 Medulloblastoma
Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq
DSpace@MIT (Massachusetts Institute of Technology) 2017cited by 57position: middle
Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma
SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b
Single-Cell Transcript Profiles Reveal Multilineage Priming in Early Progenitors Derived from Lgr5+ Intestinal Stem Cells
Sox2 Suppresses Gastric Tumorigenesis in Mice
Assessment of ABT-263 activity across a cancer cell line collection leads to a potent combination therapy for small-cell lung cancer
Inhibition of mutant EGFR in lung cancer cells triggers SOX2-FOXO6-dependent survival pathways
Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells
The Genomic Landscape of Pediatric Ewing Sarcoma
Single-Cell RNA Sequencing Identifies Extracellular Matrix Gene Expression by Pancreatic Circulating Tumor Cells
EWS-FLI1 Utilizes Divergent Chromatin Remodeling Mechanisms to Directly Activate or Repress Enhancer Elements in Ewing Sarcoma
An Aberrant Transcription Factor Network Essential for Wnt Signaling and Stem Cell Maintenance in Glioblastoma
The <i>IGF2</i> intronic miR-483 selectively enhances transcription from <i>IGF2</i> fetal promoters and enhances tumorigenesis
High-Throughput Tyrosine Kinase Activity Profiling Identifies FAK as a Candidate Therapeutic Target in Ewing Sarcoma
The WTX Tumor Suppressor Enhances p53 Acetylation by CBP/p300